WashU Pan-Cancer miRNome Atlas

 

Search by miRNA
  Tumor Development
  Tumor Stage and Grade
  • Survival Outcome
  • Expression Profile
Search by Cancer Type
  Tumor Development
  Tumor Stage and Grade
  Survival Outcome
  • Expression Profile
Search for miRNA-Target Correlation
  Search by miRNA
  Search by Gene
Survival Signature Analysis
  Pre-calculated signatures
  Custom signatures
Clustering Analysis
  Hierarchical clustering
  K-means clustering
Help|Walkthrough
    
Search miRNA for significance in survival
Input miRNA using full 3p/5p name:
Example submission
Select a significance threshold:
P <  
     

Search by a full miRNA name to retrieve a list of cancer types where patient survival is closely associated with expression of the selected miRNA.

Significance is determined independently in two manners.

The log rank p-value results from a univariate Cox analysis, whereby miRNA expression is evaluated in response to patient survival time. Univariate Cox analysis also provides a z-score, which weighs the importance of the miRNA in response to these parameters.
The t-test p-value is generated from the Student's t-test, based on patient vital status. Log2 mean expression of the miRNA in the two survival cohorts are also provided.

The limits on significance can be increased or decreased to expand or contract results, respectively.